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August 14, 1967

Regular, Filter-Tip, and Modified Cigarettes: Nicotine Excretion, Free Fatty Acid Mobilization, and Catecholamine Excretion

Author Affiliations

From the Division of Cardiology, Philadelphia General Hospital.

JAMA. 1967;201(7):545-546. doi:10.1001/jama.1967.03130070065021

A recent report from the Roswell Park Memorial Institute, at Buffalo,1,2 stated that filter-tip cigarettes did not effectively remove tars and nicotine from cigarette smoke. The study was based on an analysis of the tar and nicotine content of the smoke of nine brands of filter-tip cigarettes, and it was concluded that filters did not protect the smoker against the health hazards of smoking.

We have previously investigated certain biochemical and pharmacological effects of cigarette smoking3-6 and felt it would be of interest to determine the influence of filters and other cigarette modifications on these effects. This report presents the results of a comparative study of the effect on nicotine excretion, free fatty acid (FFA) mobilization, and catecholamine excretion of regular and filter-tip cigarettes, pipe tobacco cigarettes, and lettuce leaf cigarettes.

Method of Study.—  Six normal men, ages 28 to 45, participated in this study. All were habitual