In an unusual family, four of five siblings had extensive bronchiectasis of the middle lobe. Three have undergone lobectomy and the fourth will probably require a resection. A strong history of allergy is present in both affected and nonaffected members of the family. Although some possible congenital and acquired factors have been investigated, the cause of the middle lobe disease in this family remains unknown.
Danielson GK, Hanson CW, Cooper EC. Middle Lobe Bronchiectasis: Report of an Unusual Familial Occurrence. JAMA. 1967;201(8):605–608. doi:10.1001/jama.1967.03130080047010
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: