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Article
August 28, 1967

Multiple Gastric Argentaffinomas

JAMA. 1967;201(9):706-707. doi:10.1001/jama.1967.03130090070028
Abstract

To the Editor:—  At exploratory laparatomy a large number of tumors were seen in the body of the stomach. Frozen sections from four of the masses all showed typical carcinoids. More than 40 carcinoid tumors were found in the resected part of the stomach, the smallest measuring 2 ml, the largest 5×4×2 cm. No muscle invasion was present. The regional nodes were normal. The patient made an uneventful recovery.

Comment:—  Several comprehensive articles describe the clinical, roentgenological, and pathological aspects of carcinoids of the stomach1-3 which originate from the Kulchitsky cell in the crypts of Lieberkuhn.4 They resemble the chromaffin cells of the paraganglia. The tumors are usually benign but metastases are reported. However, in gastric carcinoids the reported incidence of metastases is almost 30%,2 most commonly in the regional lymph nodes, and less frequently in the liver. Long-term survivals are common in the presence of metastases

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