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August 28, 1967

Septal Defect Related to Intrauterine Hypothermia

Author Affiliations

Los Angeles

JAMA. 1967;201(9):708-709. doi:10.1001/jama.1967.03130090072031

To the Editor:—  Recent reports suggest that the effect of hypothermia on the unborn child is relatively benign both in humans1-4 and in animals. However, no report of a long-term evaluation of a child subjected to hypothermia in utero has been made. The present case report records a five-year follow-up of a child subjected to 69 hours of induced hypothermia (29.8 to 32 C) at 12 to 14 weeks of fetal life. The child was eventually found to have a ventricular septal cardiac defect.

Report of a Case:—  A 19-year-old single Oriental woman was brought to the University of California, Los Angeles (UCLA) emergency room, comatose. On the day of admission, a friend attempted an abortion by inserting a rectal tube into the vagina and blowing forcefully through the tube several times. The patient became suddenly unresponsive. At the emergency room she had a temperature of 37 C, pulse