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Sept 4, 1967

Poliomyelitis Associated With Type 2 Virus: Paralytic Disease in the Father of a Recently Immunized Child

Author Affiliations

From the Division of Neurology, Department of Medicine, University of Washington School of Medicine (Dr. Swanson), Virology Laboratory, Children's Orthopedic Hospital (Dr. McAlister), and the Seattle—King County Health Department (Dr. Peterson), Seattle.

JAMA. 1967;201(10):771-773. doi:10.1001/jama.1967.03130100069023

Paralytic poliomyelitis was diagnosed clinically in a 29-year-old man three weeks after his 2-year-old son received trivalent live oral poliovirus vaccine. Type 2 poliovirus with "vaccine-like" characteristics was isolated from the patient's stool, and the serum showed a significant rise in neutralizing antibody against type 2 virus. There was no rise in complement fixation antibody titers. The patients illness was likely due to type 2 poliovirus contracted from his son. Physicians should inquire about the immunization status of parents before administering vaccine to children.