Renal homotransplantation has been successful in a patient with rapidly progressive glomerulonephritis. This patient had normal serum complement levels at the time of operation. Since the serum complement concentration has been shown to parallel the activity of acute glomerulonephritis, normal complement levels would appear to indicate the disease was essentially inactive at the time of surgery. The results in this case support the conclusion that the activity of the preexisting glomerulonephritis plays an important role in the survival and function of the transplanted kidney.
Costa C, Maloney PJ, Wilkerson JA, Martin DC. Renal Homotransplantation: Successful Course Following Rapidly Progressive Glomerulonephritis. JAMA. 1967;201(13):1044–1047. doi:10.1001/jama.1967.03130130070021
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: