[Skip to Content]
[Skip to Content Landing]
Sept 25, 1967

Renal Homotransplantation: Successful Course Following Rapidly Progressive Glomerulonephritis

Author Affiliations

From the departments of internal medicine (Dr. Costa), urology (Drs. Maloney and Martin), and pathology (Dr. Wilkerson), University of California, Los Angeles, School of Medicine. Dr. Costa is now at the University of Rio Grande do Sul, Porto Allegre R.S., Brazil. Dr. Costa was a fellow of the Kellogg Foundation, and Dr. Maloney was a fellow of the McLaughlin Foundation.

JAMA. 1967;201(13):1044-1047. doi:10.1001/jama.1967.03130130070021

Renal homotransplantation has been successful in a patient with rapidly progressive glomerulonephritis. This patient had normal serum complement levels at the time of operation. Since the serum complement concentration has been shown to parallel the activity of acute glomerulonephritis, normal complement levels would appear to indicate the disease was essentially inactive at the time of surgery. The results in this case support the conclusion that the activity of the preexisting glomerulonephritis plays an important role in the survival and function of the transplanted kidney.