Previous studies of the treatment of nongonococcal urethritis (NGU) have generally not been closely controlled, and have often produced conflicting results. In the present study, 96 men with NGU were treated with placebo or tetracycline hydrochloride while "confined" aboard an aircraft carrier at sea. A seven-day tetracycline regimen was more effective than a four-day tetracycline regimen or placebo in the short-term cure of NGU.
Holmes KK, Johnson DW, Floyd TM. Studies of Venereal Disease: III. Double-Blind Comparison of Tetracycline Hydrochloride and Placebo in Treatment of Nongonococcal Urethritis. JAMA. 1967;202(6):474–476. doi:10.1001/jama.1967.03130190080010
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: