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May 19, 1975

Malignant Melanoma in Husband and Wife

Author Affiliations

Salt Lake City
Twin Falls, Idaho

JAMA. 1975;232(7):705-706. doi:10.1001/jama.1975.03250070007003

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To the Editor.—  Robertson (217:1553, 1971) reported the contemporaneous occurrence of melanomas in a husband and wife; a second similar report was made by Robinson and Manheimer (220:277, 1972); and Baumar reported melanomas occurring about the same time in a brother and his adopted stepbrother (218:1300, 1971).The present report is of a young couple who both died of melanoma with cerebral metastases within a two-year period, leaving behind four small children.The wife, a 31-year-old, obese, fair-complexioned female, had a mole on her right calf during her entire life. In February 1968, this mole became inflamed and appeared to be infected. On June 23, 1968, she went to her family physician, who performed an excision biopsy. The pathologic diagnosis was malignant melanoma with lymphatic invasion and extension to the surgical margin. Results of a complete blood cell (CBC) count, urinalysis, 12-channel survey, chest x-ray examination, and VDRL test were all