Individuals with ultimately middle to low normal-range levels of serum uric acid and cholesterol demonstrated highly significant rises in these serum fractions during specific stages of a four-month underwater demolition training period. Serum urate concentration was elevated during periods of apparent anticipation of a demanding situation while cholesterol levels rose concomitant with a period of particular psychological stress. Serum urate concentration demonstrated a significant fall during a period of quite intense psychological stress.
Rahe RH, Arthur RJ. Stressful Underwater Demolition Training: Serum Urate and Cholesterol Variability. JAMA. 1967;202(11):1052–1054. doi:10.1001/jama.1967.03130240094022
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