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December 18, 1967

Peritoneal Dialysis in Quinine Sulfate Intoxication

Author Affiliations

From the Department of Internal Medicine and the Institute of Industrial Health, University of Michigan, Ann Arbor. LCDR Markham is now at the Submarine Medical Center, Groton, Conn, and Dr. Eckberg is now at the National Institutes of Health, Bethesda, Md.

JAMA. 1967;202(12):1102-1103. doi:10.1001/jama.1967.03130250084021

Early cinchonism developed in an 18-year-old girl after the ingestion of 3.84 gm of quinine sulfate, in an attempt to induce abortion. Initially, the exact dose was unknown and she was treated with peritoneal dialysis. Although dialysis was begun after the peak plasma levels had passed, 415 mg (10.8%) were recovered in the dialysate fluid over the next 16 hours.