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December 18, 1967

An Introduction to the Haemoglobinopathies and the Methods Used for Their Recognition

JAMA. 1967;202(12):1110. doi:10.1001/jama.1967.03130250092031

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This book offers the "core material" pertaining to hemoglobin structure and genetic abnormalities in a brief, well-written and accurate monograph. The author does an excellent job of concisely and clearly summarizing a field that is continuously altered by rapid advances in protein chemistry and genetics. Further, he tells you how this new knowledge is helpful in gaining a better understanding of the variable clinical syndromes associated with hemoglobinopathies.

The methods section is only 16 pages, yet it includes an organized approach to the evaluation of a suspected hemoglobin abnormality. Those methods not presented in sufficient detail to perform directly are adequately referenced.

The medical student would benefit from reading this, but the monograph is best suited for the resident physician receiving special training in hematology or for the practicing physician with an interest in hematology. The monograph offers the careful reader an opportunity to gain an excellent perspective of a