Lesions that were felt to represent ganglia of the wrist developed in two patients. The histologic features of these lesions were atypical, and four years later rheumatoid arthritis developed in both patients. It is suggested that rheumatoid ganglia may occur as an isolated finding and when such lesions are discovered, the physician should be alerted to the possible future development of rheumatoid arthritis.
Croft JD, Jacox RF. Rheumatoid "Ganglion" as an Unusual Presenting Sign of Rheumatoid Arthritis. JAMA. 1968;203(2):144–146. doi:10.1001/jama.1968.03140020072019
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