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February 19, 1968

Stramonium and Belladonna Hallucinogens

Author Affiliations

Newton, NJ

JAMA. 1968;203(8):606. doi:10.1001/jama.1968.03140080066025

To the Editor:—  I read with great interest the report of David J. Muller, MD, concerning the use of "Unpublished Hallucinogens" (202:650, 1967) but must disagree with his statement that this is a "new" use of belladonna alkaloids mixed with stramonium.The mixture referred to by Muller is a 50.4% stramonium and 4.5% belladonna preparation. The predominance of stramonium in this large a proportion is probably the cause of the psychotomimetic effect. The use of this preparation as a hallucinogen has been reported by Dean.1 Cavanagh also makes reference to this preparation in a recent article directed to the clergy.2I strongly agree with Muller in his assertion that the mixture should be controlled. But he may be jumping the gun in believing that the belladonna alkaloids are being used on a wide basis as hallucinogens. Stramonium is from the plant Datura stramonum and belladonna is from