"Calcitonin" or "thyrocalcitonin"? Both names are vying for acceptance. "Calcitonin" is the name given to the calcium-lowering hormone by Copp and his co-workers1 at the University of British Columbia when, in 1962, they postulated its existence on the basis of perfusion experiments on canine thyroid-parathyroid complexes. The Canadian investigators believed that this hormone was secreted by the parathyroid glands, but, avoiding commitment to an anatomic site, they chose a functional term. One year later Hirsch and his associates2 discovered a hypocalcemic, hypophosphatemic principle in thyroid tissue from which they were able to extract a potent biological preparation. For this they devised a simple bio-assay in which an injection of the test substance was given to rats, and the one-hour fall in plasma calcium levels was taken as the response. They named the substance "thyrocalcitonin," and, when it was subsequently demonstrated that thyrocalcitonin and calcitonin were in fact identical,
THE TONINS OF CALCIUM. JAMA. 1968;203(11):976–977. doi:10.1001/jama.1968.03140110068016
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