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March 25, 1968


JAMA. 1968;203(13):27-38. doi:10.1001/jama.1968.03140130069034

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Evidence Growing That Cancer 

Cells May Be Turned Against Themselves  Evidence is mounting that cancer cells, usually cast in the role of exploiters, are themselves potentially exploitable."We are surely justified," says R. Lee Clark, MD, "in the conviction that intimate knowledge of the many factors involved in expression and replication of genetic information will lead to methods for suppression and repression of cells seeking to escape normal control mechanisms of the body."Earlier this month, Dr. Clark welcomed many of the leading investigators in this area to a symposium at the University of Texas' M.D. Anderson Hospital and Tumor Institute, Houston, where he is director and surgeon-in-chief.Among them was Sol Spiegelman, PhD, who—with other University of Illinois investigators—provided the first example four years ago of a genetic material directing its own reduplication in the test tube.This work, involving the MS-2, and later the Q-Beta, RNA