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April 1, 1968

Hemorrhagic Pleural Effusion in Meigs' Syndrome

JAMA. 1968;204(1):81-82. doi:10.1001/jama.1968.03140140083030

To the Editor:—  Meigs' syndrome is a disorder characterized by ascites and hydrothorax in association with a benign tumor of the ovary. The absolute criterion for the diagnosis of Meigs' syndrome is the spontaneous disappearance of the ascites and hydrothorax after removal of the tumor.1In 1964 Mazzlin and Stevens2 collected all the cases of Meigs' syndrome reported in the literature and, adding one of their own, found a total number of 129. The syndrome is thus rare, but recognition is important since it is curable.It is the purpose of this report to call attention to the rare occurrence of a hemorrhagic effusion in Meigs' syndrome. The fluid in Meigs' syndrome is nearly always described as being a clear yellow transudate with a low specific gravity and low protein content.3 There have been only nine cases reported in which the fluid was hemorrhagic.3-5

Report of