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April 1, 1968

Progress in Medical Genetics

Author Affiliations

Nashville, Tenn

JAMA. 1968;204(1):83. doi:10.1001/jama.1968.03140140085036

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Steinberg and Bearn have again succeeded in putting together a diverse and instructive collection of papers on human genetics in the fifth volume of this excellent series. This year's offerings include a brief but provocative essay on the nature-nurture problem by René Dubos and four scholarly reviews of the thalassemias (D. J. Weatherall), the porphyrias (J. Waldenström and Birgitta Haeger-Aronsen), the muscular dystrophies (A. E. H. Emery and J. N. Walton), and the genetic hepatopathies (Sheila Sherlock). Every reader will have his own favorite, but it is hard to imagine a more informative and concise review of such a complex and important field as the thalassemias than Weatherall's 49-page summary. The evidence for clinical and genetic heterogeneity is clearly set forth; however, there is as yet no evidence for the existence of γ thalassemia, as an unfortunate and confusing typographical error may lead the reader to believe.

This volume can