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April 15, 1968

Disulfiram—Alcohol Side Effects

JAMA. 1968;204(3):272. doi:10.1001/jama.1968.03140160081030

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To the Editor:—  I certainly do agree with the tenor of what Dr. Fox says regarding the use of disulfiram and would like to state very clearly that I continue to use it and strongly believe in it as an adjunct in the treatment of alcoholism. I reported the reaction since I felt that it was quite a striking one and because the reaction occurred in an individual who was not by any means otherwise psychotic.The individual on which I reported had functioned well in the community prior to that episode, which was the first and only one of its kind for him. There have been none since. As a matter of fact, I am not sure that he could have been classified as an alcoholic in the usual sense, but instead as a "heavy drinker." More recently, I have been using disulfiram with people who are not alcoholics,