This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
To the Editor.—
I was intrigued by the recent case report by Shelley, "Essential Progressive Telangiectasia: Successful Treatment with Tetracycline" (216:1343, 1971)—of a patient with this rare entity whose lesions cleared completely within a period of three months following the administration of tetracycline hydrochloride orally in a dose of 250 mg four times a day. In this 39-year-old woman, repeated general physical examinations had been noncontributory. The eruption, consisting of confluent areas of erythema and dilated capillaries, had begun on the tops and sides of the feet seven years previously and had gradually extended onto the ankles, legs, and thighs. Shelley was unable to explain the mechanism of action of tetracycline in this condition, feeling that it might have been on the basis of some little-understood pharmacodynamic action rather than the usual wide-spectrum antibiotic effect, although he speculated that a change in bowel flora must also be considered as
Ayres S. Tetracycline Treatment of Telangiectasia. JAMA. 1971;217(10):1392. doi:10.1001/jama.1971.03190100074025
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: