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June 17, 1968

Conversion of Polycythemia Vera to Chronic Di Guglielmo's Syndrome

Author Affiliations

From the Department of Medicine, Stanford University School of Medicine, Palo Alto, Calif, and the University of California, San Francisco. Dr. Eastman was a fellow in hematology at the Stanford University of Medicine.

JAMA. 1968;204(12):1141-1143. doi:10.1001/jama.1968.03140250121021

A patient with polycythemia vera was treated with sodium phosphate P 32. The polycythemia vera converted to chronic Di Guglielmo's syndrome, with dwarfed binucleate megakaryocytes, and the patient died of acute myeloid leukemia.