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November 8, 1971

Methadone-Induced Pulmonary Edema

Author Affiliations

From the Department of Medicine, University of Colorado Medical Center, Denver.

JAMA. 1971;218(6):882-883. doi:10.1001/jama.1971.03190190068019

A 19-year-old former heroin addict developed pulmonary edema within six hours after the oral ingestion of 80 mg of methadone hydrochloride and recovered rapidly and without sequalae, with vigorous ventilatory support. This complication has been observed following intravenous overdosage with morphine and heroin, but has not previously been recorded after methadone ingestion.