[Skip to Content]
[Skip to Content Landing]
July 8, 1968

Death Associated With Ventricular Arrhythmia and Thioridazine Hydrochloride

Author Affiliations

From the Department of Medicine, US Army Hospital Specialized Treatment Center, Fort Gordon, Ga.

JAMA. 1968;205(2):108-110. doi:10.1001/jama.1968.03140280062021

Ventricular arrhythmia associated with the administration of thioridazine hydrochloride is thought to be the cause of death of a 19-year-old boy. There were changes in the repolarization portion of the electrocardiogram. High doses of thioridazine had been given in cases with fatal or nearly fatal outcomes, and there is a strong suggestion that when high doses of phenothiazines are required, thioridazine should be considered contraindicated.