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July 15, 1968

The Skin and Internal Disease

Author Affiliations

New Orleans

JAMA. 1968;205(3):189. doi:10.1001/jama.1968.03140290081035

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The physician who seeks facts about the cutaneous lesions accompanying a systemic disease will probably find them either in this book or in the long lists of references following most of its 14 chapters. Good descriptions abound, but the text, comprising subject matter from 18 contributors, lacks cohesion. Nonetheless, this book packs a lot of information into a small space.

The chapter devoted to pigmentary changes clearly outlines the metabolic errors and describes the clinical findings in phenylketonuria and alkaptonuria. Pellagra and acanthosis nigricans also receive appropriate emphasis. And an interesting section discusses and illustrates the cutaneous lesions of mycosis fungoides, leukemia, lymphoma, and Kaposi's sarcoma. The other chapters describe the appearances of the skin in a variety of diseases ranging from porphyrinuria to endocrine disorders.

Though usually noting physiologic and pathologic changes, sometimes in considerable detail, the contributors emphasize mostly clinical findings. Many of their illustrations are good and