Fever associated with severe hypoglycemia was observed on 16 occasions in 14 patients. In most instances treatment with glucose failed to bring about prompt recovery of consciousness. Evidence suggests that both fever and delay in response to treatment are related to the presence of cerebral edema which may respond to treatment when appropriate measures, such as intravenous administration of mannitol are taken.
Ramos E, Zorilla E, Hadley WB. Fever as a Manifestation of Hypoglycemia. JAMA. 1968;205(8):590–592. doi:10.1001/jama.1968.03140340060019
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