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April 10, 1972

Evaluation of γ-Glutamyl Transpeptidase in Myocardial Infarction

JAMA. 1972;220(2):217-219. doi:10.1001/jama.1972.03200020035009

The activity of γ-glutamyl transpeptidase (γ-GTP) was determined serially in 64 patients with suspected myocardial infarction. Of 38 patients with proved myocardial infarction, only four showed early change of y-GTP activity and six showed change between the fifth and seventh day. Of 26 patients shown not to have myocardial infarction, slightly over one-third had persistent false-positive elevation of γ-GTP. These studies failed to demonstrate a significant value to this enzyme determination.