[Skip to Content]
[Skip to Content Landing]
February 2, 1976

Coombs-Positive Hemolytic Uremic Syndrome

Author Affiliations

From the Division of Nephrology and Hypertension, University of Louisville School of Medicine, Louisville. Dr Zeis is now with the Department of Pediatrics, the University of Illinois Hospital, Chicago.

JAMA. 1976;235(5):522-523. doi:10.1001/jama.1976.03260310036019

Two children presenting typical clinical features of the hemolytic-uremic syndrome had a positive direct Coombs test that remained positive throughout the illness. It is probable that an upper respiratory tract infection precipitated an antigen-antibody reaction that caused the autoimmune hemolytic anemia and immune-complex glomerulonephritis.

(JAMA 235:522-523, 1976)