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July 31, 1972

Intraperitoneal Extravasation of Urine: BUN/Serum Creatinine Disproportion

Author Affiliations

From the Department of Urology (Dr. Sullivan), University of California at Davis, and the Division of Urology (Drs. Lackner and Banowsky), University of New Mexico, Albuquerque.

JAMA. 1972;221(5):491-492. doi:10.1001/jama.1972.03200180033008

Two patients with nontraumatic bladder rupture and intraperitoneal extravasation of urine were found to have an elevation of blood urea nitrogen (BUN) content disproportionate to the normal or mildly elevated serum creatinine value. In the absence of other causes for this disproportion, and supported by observations on BUN and creatinine removal in peritoneal dialysis, it is suggested that in azotemic subjects a ratio of BUN to creatinine level far in excess of the mean figure of 10.8 to 1 may occur as a result of intraperitoneal extravasation of urine.

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