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March 22, 1976

Thyroid Scintigram: Sensitivity With Sodium Pertechnetate Tc 99m and Gamma Camera With Pinhole Collimator

Author Affiliations

From the Department of Radiation Oncology (Dr Colman), the Division of Nuclear Medicine (Drs Ryo, Arnold, and Pinsky), and the Division of Endocrinology and Metabolism (Drs Favus, Frohman, Schneider, and Stachura), the Michael Reese Hospital and Medical Center, Chicago.

JAMA. 1976;235(12):1235-1238. doi:10.1001/jama.1976.03260380029021

To evaluate the reliability of thyroid scintigraphy in the diagnosis of nodular growths, scintigrams of patients who later underwent thyroidectomy were reviewed and correlated with pathologic findings. The scintigrams were all obtained with a 5-mm single-hole collimator-equipped gamma-scintillation camera after intravenous injection of 5 millicuries of sodium pertechnetate Tc 99m.

In the group of 92 patients, six of whom had two histologically different lesions, 149 nodules were identified pathologically. There were 26 nodules 2 to 5 mm in diameter, of which 22 were benign and four were malignant. None of the 22 benign nodules were delineated scintigraphically.

Superior image quality and resolution, low radiation dose, technical simplicity, and speed make Tc pinhole-camera scintigraphy the best procedure available for routine thyroid imaging.

(JAMA 235:1235-1238, 1976)