IN HIS treatise on diseases of the urinary tract, Samuel D. Gross,1 in 1855, noted that cancer of the prostate was considered to be extremely rare. He sided with this point of view and, except for anodynes and leeches applied to the perineum, considered cancer of the prostate as not amenable to treatment. Toward the end of the 19th century, individual case reports appeared in the literature.2 In the 1900s, Albarrán and Hallé3 found carcinoma in 14 of 100 surgical specimens of prostatectomy for benign prostatic hypertrophy. It is of interest that this coincided with the observation, also made by Albarrán,4 that bilateral orchiectomy frequently provided improvement to patients with "benign prostatic hypertrophy."
Among all nations, the United States has the highest incidence of cancer of the prostate. The Third National Cancer Survey (1969 to 1971)5 showed that the age-adjusted incidence in US males (60.8/100,000
del Regato JA. Cancer of the Prostate. JAMA. 1976;235(16):1727–1730. doi:10.1001/jama.1976.03260420043032
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