One of the most serious problems among women using the intrauterine device (IUD) has been pelvic inflammatory disease (PID). Subjects for the present investigation were chosen from 15- to 44-year-old women seeking emergency medical attention at a large city hospital. Febrile and afebrile patients with PID and appropriate controls were asked to complete a self-administered questionnaire concerning their demographic, reproductive, and contraceptive histories. Results showed a significantly higher proportion of IUD users among febrile cases of PID (38%) than among controls (11%). This implies that febrile PID is five times as likely to develop in an IUD user as in a nonuser.
(JAMA 235:1851-1853, 1976)
Faulkner WL, Ory HW. Intrauterine Devices and Acute Pelvic Inflammatory Disease. JAMA. 1976;235(17):1851–1853. doi:10.1001/jama.1976.03260430021016
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