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November 13, 1972

Pharmacology of the Cerebral Circulation

JAMA. 1972;222(7):840. doi:10.1001/jama.1972.03210070070034

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This multiauthored book, extremely broad in scope, is divided into 12 informative chapters, useful to both the clinician and the researcher. It is unusual for a text concerned with pharmacology to be largely directed to the physiological, physiopathological, and clinical therapeutic aspects of brain circulation. These discussions emphasize the void still existing in the pharmacology of brain circulation. The editor points out that central nervous system stimulants or depressants are known to cause obvious changes in cerebral blood flow; however, the mechanisms involved in these effects are not always clearly defined. Nonetheless, the discussions of the pharmacology involved in brain circulation is extensive, detailed, complete, and accompanied by more than adequate bibliographies.

Of particular interest to the neurologist, neurosurgeon, and pharmacologist, the book has value for other medical specialists. The chapter on central nervous system depressants with its excellent discussions of the cerebrovascular effects of anesthetics should appeal to the