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May 17, 1976

Medical News

JAMA. 1976;235(20):2179-2185. doi:10.1001/jama.1976.03260460003001

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Prostaglandin analogue device used for inducing abortions  Abortion can be induced successfully during the first and second trimesters of pregnancy by a newly developed intravaginal device of silicone rubber that contains a prostaglandin analogue.The disk-shaped device is impregnated with 11 mg of 0.5% 15 (S)-15-methyl prostaglandin F2α methyl ester. It has a surface area of 20 sq cm and is approximately 0.2 cm thick and weighs 2.2 gm. The device is inserted high into the vaginal vault (without prior cleaning of the vagina), followed by a tampon to prevent expulsion. Patients are kept in a supine position for at least 30 minutes.This new method of inducing abortion is being studied by Niels H. Lauersen, MD, associate professor of obstetrics and gynecology and Kathleen H. Wilson, a research assistant, at the New York Hospital-Cornell University Medical College in New York.At the Las Vegas meeting of the