Anasarca with pronounced hypoalbuminemia developed in a young woman 15 months after the onset of a mild, arthralgic type of systemic lupus erythematosus (SLE) without evidence of active nephritis. Investigation indicated a gastrointestinal rather than a renal site for protein loss. A full clinical remission was achieved with low-dose corticosteroid therapy.
(JAMA 236:287-288, 1976)
Trentham DE, Masi AT. Systemic Lupus Erythematosus With a Protein-Losing Enteropathy. JAMA. 1976;236(3):287–288. doi:10.1001/jama.1976.03270030041027
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