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Tetracycline remains a useful drug in the treatment of amebiasis, but paromomycin sulfate is more effective gram for gram. Few patients whom my colleagues and I have treated with two grams of tetracycline daily for various diseases could tolerate the program for more than a week. Perhaps patients receiving high doses of tetracycline do not complain about their diarrhea to their dermatologists, but rather to their internists.
KEAN BH. Tetracycline-Reply. JAMA. 1976;236(4):344. doi:10.1001/jama.1976.03270040010006
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