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August 2, 1976

Hodgkin's Disease

JAMA. 1976;236(5):513. doi:10.1001/jama.1976.03270050057038

Of all the many illnesses encompassed by the word "cancer," perhaps none is more challenging to the medical practitioner than Hodgkin disease. Basic and applied research and thoughtful clinical observation have enabled the physician to offer potentially curative treatment in many cases and meaningful palliation in most others. With his coauthors, Dr Lacher surveys in considerable detail the current state of the art and the science of management of this complex disease.

Schottenfeld provides a concise and yet detailed overview of the epidemiology of Hodgkin disease, which poses more questions than answers. Several chapters on diagnostic methods and staging procedures by Ultmann and others present an exciting but obviously demanding script for the physician to follow in attempting to define the type and extent of disease involvement. One should not overlook the discussion of splenectomy and the controversy over its role in the staging evaluation of patients with Hodgkin disease.