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September 6, 1976

Amebiasis of Clitoris Mimicking Carcinoma

Author Affiliations

From the departments of pathology and laboratory medicine (Drs Majmudar and Lee), and gynecology and obstetrics (Dr Chaiken), Emory University School of Medicine at Grady Memorial Hospital, Atlanta.

JAMA. 1976;236(10):1145-1146. doi:10.1001/jama.1976.03270110043028

AMEBIC infection of the genital tract is rare, even in countries where intestinal amebiasis is endemic. To our knowledge, 75 cases of amebiasis of the female genital tract have been reported in the English literature,1-10 only six of them being from the United States.1-3 The last reported case of genital amebiasis from this country was in 1954.3 Furthermore, although cervical, vaginal, and vulvar amebiasis has been reported, a case of exclusive clitoral involvement has not been previously cited.

Report of a Case  A 48-year-old woman came to the out-patient clinic of the Grady Memorial Hospital with a nine-month history of a painful and pruritic vulvar lesion. Her physician had treated her with nystatin suppositories, but she failed to improve. She denied any gastrointestinal, genitourinary, and systemic symptoms, except for a burning micturition.

Clinical Findings.—  In the clitoral region, there was a well-circumscribed, greyish-white, slightly elevated, fungating lesion