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October 11, 1976

Antilymphoblast Globulin in Renal Transplant Patients: No Allergic Reactions

Author Affiliations

From the Department of Internal Medicine, Mayo Clinic, Rochester, Minn (Dr Martin); and the departments of medicine (Dr Blumenthal and Ms Roitman) and surgery (Drs Condie, Simmons, and Najarian), University of Minnesota Hospitals, Minneapolis.

JAMA. 1976;236(15):1729-1731. doi:10.1001/jama.1976.03270160051032

The incidence and type of allergic reactions to antilymphoblast globulin (ALG) and their relationship to skin testing, histamine release, and serum levels of ALG and anti-ALG antibodies were studied prospectively in 50 patients receiving high-dose ALG therapy intravenously for the first two weeks after renal transplantation. No clinically apparent allergic reactions occurred in the patients studied.

(JAMA 236:1729-1731, 1976)