Vaccination was well tolerated by 93 patients with multiple sclerosis who received a total of 209 doses of influenza vaccine. In one patient, evidence of a new lesion developed after vaccination; the relapse rate was less than would be expected in the natural course of the illness. Toxic and allergic reactions appeared with 7% and 0.5% of the vaccinations, respectively—a rate no higher than that observed in the general population.
(JAMA 236:1965-1966, 1976)
Sibley WA, Bamford CR, Laguna JF. Influenza Vaccination in Patients With Multiple Sclerosis. JAMA. 1976;236(17):1965–1966. doi:10.1001/jama.1976.03270180041018
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