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February 7, 1977

Blood Amylase and Diabetic Ketoacidosis

JAMA. 1977;237(6):532. doi:10.1001/jama.1977.03270330022010

To the Editor.—  The patient whose case was reported by vanSonnenberg and Pitchumoni (236:482, 1976) has some similarities to the case reported by Block et al.1 Apparently vanSonnenberg and Pitchumoni did not examine the serum of their patient for a macroamylase, and no values for urinary amylase are given after the sixth day of hospitalization. From the clinical course and the laboratory data, it would seem reasonable to consider the possibility of long-existent macroamylasemia, possibly with superimposed pancreatic derangement during the episode of diabetic ketoacidosis.