This communication reports cases of 16 women in whom cancer of the breast developed after radiation therapy for acne or hirsutism, suggesting another group at higher risk than is generally expected for cancer of the breast. It is prudent to regard the carcinogenic effect of radiation on the breast as proportional to dose without a threshold. Mammography in young women should be ordered only selectively, not for screening.
(JAMA 237:789-790, 1977)
Simon N. Breast Cancer Induced by RadiationRelation to Mammography and Treatment of Acne. JAMA. 1977;237(8):789–790. doi:10.1001/jama.1977.03270350049020
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