A 38-year-old woman had papillary carcinoma of the thyroid when surgery for adenomatous goiter was performed 20 years after treatment of hyperthyroidism with sodium iodide I 131. To our knowledge, this is the ninth reported case of microscopically proved cancer following such therapy, and it is the one with the longest interval since treatment.
Kreps EM, Kreps SM, Kreps SI. Treatment of Hyperthyroidism With Sodium Iodide I 131Carcinoma of the Thyroid After 20 Years. JAMA. 1973;226(7):774–775. doi:10.1001/jama.1973.03230070038008
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