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February 28, 1977

Medical News

JAMA. 1977;237(9):847-856. doi:10.1001/jama.1977.03270360009001

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Blood test may start new era in diabetes therapy evaluation  A new laboratory test developed at Children's Hospital Medical Center, Boston, may provide a definitive means of telling whether the adequacy of long-term blood glucose control in the diabetic patient has any relationship to the progression of various diabetic complications. This has been a controversial matter in the field of diabetes for some time.Other possible applications of the glycosylated hemoglobin test include assessment of the effectiveness, over time, of various current methods of therapy, such as short- and long-acting insulins and oral hypoglycemic agents. Future methods of treatment such as islet cell transplantation and use of an artificial pancreas may also be monitored by this test.Kenneth H. Gabbay, MD, associate professor of pediatrics at Harvard Medical School, director of the cell biology laboratory at Harvard, and associate physician (endocrine division), Children's Hospital Medical Center, discussed the test