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February 28, 1977

Primary Lymphoma of the Lung

JAMA. 1977;237(9):895-896. doi:10.1001/jama.1977.03270360057020

PRIMARY lymphoma of the lung is an uncommon yet distinct entity, histologically indistinguishable from secondary or metastatic lymphoma but biologically and behaviorally different.1 It starts extranodally within the lymphatic tissues of the lung, spreads slowly by contiguity, produces few or no symptoms, and usually can be cured. The following case illustrates primary lymphoma of the lung.

Report of a Case  During a routine investigation, a 59-year-old man was found to have an abnormal chest x-ray film. He denied any symptoms, had smoked a pipe for many years, and considered himself in good health. Results of physical examination, routine and customary laboratory studies, and bronchoscopy were normal. Frontal and lateral roentgenograms of the chest showed a homogeneous, poorly marginated density confined to the right middle lobe (Figure). Tomograms of the lung showed a normal, patent, tracheobronchial tree and an air bronchogram within the right middle lobe. Studies of the sputum