To the Editor.—
The SPECIAL COMMUNICATION entitled "Estrogens and Menopause" by Carol M. Proudfit, PhD (236:939, 1976), while timely, contains data that, if incorrect, could well have misled the author and resulted in erroneous conclusions in the final paragraph. The data that I question were attributed to Austin (reference 5). Since I am not privy to Austin's communication, I cannot tell if the difficulty lies in a typographical error, a misinterpretation, or a unique endometrial cancer problem in California.An incidence of invasive carcinoma of the uterus of 180/100,000 population as reported would not seem likely, even if cancer of the cervix were included. Although it is not entirely clear, I presume the author is referring to only carcinoma of the corpus. Even an incidence rate of 100/100,000 population, which is the rate from which endometrial cancer allegedly increased (1969 vs 1974), would appear to be from four to five times
Christopherson WM. Estrogens and Endometrial Cancer. JAMA. 1977;237(10):958. doi:10.1001/jama.1977.03270370030005
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