[Skip to Content]
[Skip to Content Landing]
March 7, 1977

Mollaret Meningitis

JAMA. 1977;237(10):960-961. doi:10.1001/jama.1977.03270370032012

To the Editor.—  Regularly repetitive episodes as a feature of Mollaret meningitis escape attention in articles on the subject. In case 3 of the report by Haynes et al (236:1967, 1976), three-day episodes recurred bimonthly. In articles cited in the communication, episodes came predictably: every 10 to 12 days (Hermans et al1), every two weeks (Tynes et al2), and every 17 to 18 days (Haynes et al). According to Bruyn et al,3 "the attacks will occur regularly, with intervals ranging from some weeks to months," as noted in their patients.Gledhill et al,4 whose patient had monthly episodes, agreed with my proposal that Mollaret meningitis may be another periodic disease.5 Because of its inflammatory nature, colchicine suppresses episodes as it does in periodic peritonitis. The beneficial effect may represent a therapeutic response, not a spontaneous remission.Evidently, some cases of Mollaret meningitis can be included