Over an 8-year period, bacteremia due to group A β-hemolytic Streptoccoccus developed in 49 patients in a cancer hospital. The most common underlying diagnosis was a solid tumor. This contrasts with the predominance of lymphomas and leukemias noted in other infections at the same institution. Infection of surgical wounds or cellulitis was frequently the source of bacteremia. Underlying disease, depressed white blood cell count, hypogammaglobulinemia, and advanced age all had less prognostic influence than expected.
Henkel JS, Armstrong D, Blevins A, Moody MD. Group A β-Hemolytic Streptococcus Bacteremia in a Cancer Hospital. JAMA. 1970;211(6):983–986. doi:10.1001/jama.1970.03170060047009
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