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March 21, 1977

Pediatric Nephrology, vol 2: Epidemiology, Evaluation and Therapy

JAMA. 1977;237(12):1267. doi:10.1001/jama.1977.03270390083039

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This volume is a collection of articles originally presented at the Second Annual Pediatric Nephrology Symposium organized in Miami in 1975. As such, it contains both edited, formal presentations, covering a broad range of topics in pediatric nephrology, and transcriptions of workshops on clinical, pathological, and psychological aspects of renal disease. The discussions interspersed between groups of articles provide interesting commentary on the topics previously covered.

Among the presentations that best portrayed the state of the art was the series on immunopathology. It covered in detail many aspects of pathogenesis of renal disease, with appropriate clinical examples and up-to-date bibliographies. Especially intriguing were the references to sickle-cell nephropathy as an immune complex disease caused by the patient's response to his own renal tubular epithelial antigens. The pathological studies of Bernstein on hereditary nephritides and Habib on nephrotic syndrome in infancy were also excellent in correlating the most recent analyses of