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March 28, 1977

Recurrent Hemoperitoneum Reversed by Ascorbic Acid

Author Affiliations

From the Departments of Medicine (Dr Cooke) and Surgery (Dr Milligan), Doctors' Hospital, Modesto, Calif.

JAMA. 1977;237(13):1358-1359. doi:10.1001/jama.1977.03270400062023

HEMOPERITONEUM, excluding those episodes resulting from surgically reversible conditions, is usually associated with a fatal outcome.1-3 Recurrent hemoperitoneum is, therefore, exceedingly rare, and medically reversed recurrent hemoperitoneum has not been reported.4

In the following account, a patient with multiple episodes of hemoperitoneum appears to have been cured by ascorbic acid therapy.

Report of a Case  A 48-year-old white woman, gravida 2, para 2, was hospitalized in April 1967, complaining of hypermenorrhea for one year and abdominal pain for five weeks. No unusual bleeding had occurred in association with dental extractions or episiotomies during vaginal deliveries. No easy bruisability had been noted, and no relative had experienced unusual bleeding. Her only medication had been aspirin as treatment for intermittent headaches.Examination disclosed minimal pallor and moderate abdominal distention. No angiomas were noted in the skin or mucous membranes. The uterus was enlarged. Hemoglobin level was 10.7 gm/100 ml, and