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February 23, 1970

Localized Xanthomas in Lymphedema Praecox

Author Affiliations

From the departments of internal Medicine (Dr. Woolling), dermatology (Dr. Jenkins), radiology (Dr. Dolan), and pathology (Dr. Evans), Methodist Hospital of Indianapolis.

JAMA. 1970;211(8):1372-1374. doi:10.1001/jama.1970.03170080060017

A girl, aged 14, had an extensive normolipemic xanthomatous eruption develop in one leg and foot, soon after the onset of lymphedema in the same limb. When the edema was reduced by treatment, the xanthomatous eruption greatly improved. It was speculated whether mechanical stretching of the skin might have been a factor contributing to the localized development of xanthomatosis in a xanthoma-prone individual.