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January 7, 1974

Serological Survey for Rubella and Measles Antibodies Among First Graders

Author Affiliations

From the Infectious Disease Division, Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati (Drs. Schiff and Linnemann and Ms. Shea), the Immunization Branch, Center for Disease Control, Atlanta (Dr. Witte), the Ohio State Department of Health, Columbus (Dr. Ackerman and Mr. Stapleton), and the Cincinnati Department of Health, Cincinnati (Drs. Elsea and Agna).

JAMA. 1974;227(1):49-52. doi:10.1001/jama.1974.03230140023005

A serological survey to determine susceptibility rates to rubella and measles was conducted among first graders in Cincinnati during 1972. Sixty-three percent (858) of the eligible first graders participated. The overall susceptibility rates to rubella and measles were 21% and 7%, respectively. The susceptibility rate to rubella was down from 75% found among first graders in an adjacent school district in 1968. However, the lower socioeconomic group of first graders had a significantly higher susceptibility rate. The middle socioeconomic group had a significantly higher susceptibility rate to measles. The failure rates for rubella and measles vaccines were 13% and 7%, respectively, indicating a need for follow-up serologic studies to determine persistence of vaccine-induced antibodies.